Membantu mengurangi risiko efek samping inhaler1, 2, 3, 4, 5, 6, 7.
Obat aerosol keluar dari inhaler dengan sangat cepat sehingga sering kali sangat sulit menggunakan inhaler dengan benar karena tabung logam harus ditekan bersamaan dengan saat Anda menarik napas8, 9.
Meningkatkan perawatan Anda. Obat seringkali berakhir di mulut, tenggorokan, dan lambung Anda saat menggunakan inhaler saja. Rongga penyimpan berkatup dapat meningkatkan pemberian obat ke paru-paru, tempat obat dibutuhkan, hingga 4 kali lebih banyak10.
Bayi dan semua anak yang tidak dapat menggunakan corong rongga, harus diminta untuk menggunakan masker11, 12. Masker sebaiknya nyaman di wajah, terpasang pas untuk membantu mereka menerima dosis obat inhaler yang tepat.
Untuk menggunakan corong secara efektif, anak Anda perlu menempatkan gigi dan mulutnya dengan erat di sekitar corong agar dapat menarik napas dalam dengan perlahan dan menahan napas selama beberapa detik. Anak-anak yang tak dapat melakukannya, perlu menggunakan masker.
CATATAN KAKI:
[1] Salzman G., Pyszynski D. Oropharyngeal candidiasis in patients treated with beclomethasone dipropionate delivered by metered-dose inhaler along and with Aerochamber. Journal of Allergy and Clinical Immunology, 1988; Volume 81, Issue 2: 424-428.
[2] Derendorf H., Nave R., Drollmann A., Cerasoli F., Wurst W. Relevance of pharmacokinetics and pharmacodynamics of inhaled corticosteroids to asthma. European Respiratory Journal, 2006; 28:1042-1050.
[3] Roller M., Zhang G., Troedson R.G., Leach C.L., Le Souëf P.N., Devadason S.G. Spacer inhaler technique and deposition of extra fine aerosol in asthmatic children. European Respiratory Journal, 2007; 29:299-306.
[4] Von Hollen D., Slater L., Hatley RHM. Impact of flow rate on NGI throat deposition from 3 HFA Inhaler formulations with anti-static valved holding chambers. Journal of Aerosol Medicine and Pulmonary Drug Delivery, 2013; 26(2); A45-A46.
[5] Oliveira R.F., et al. VHC performance evaluation at constant flow: 30L/min. Proceedings of the ASME2015 International Mechanical Engineering Congress and Exposition, 2015 Houston Texas.
[6] Leach C., Colice G. A Pilot Study to Assess Lung Deposition of HFA-Beclomethasone and CFC-Beclomethasone from a pressurized Metered Dose Inhaler with and without add-on spacers and using varying breath hold times. Journal of Aerosol Medicine and Pulmonary Drug Delivery, 2010; 23(6):355-361.
[7] Dickens G., et al. Pharmacokinetics of flunisolide administered via metered dose inhaler with and without a spacer device and following oral administration. Annals of Allergy, Asthma & Immunology, 2000; Volume 84, 528-532.
[8] Saunders K.B. Misuse of inhaled bronchodilator agents. Br Med J. 1965; 1:1037-1038.
[9] Oprehek J., et al. Patient error in use of bronchodilator metered aerosols. Br Med J. 1976; 1:76.
[10] Gardenhire D., Arzu A., Dean H., Myers T. A guide to aerosol delivery devices for respiratory therapists 3rd edition, American Association for Respiratory Care, 2013.
[11] Nhlbi.nih.gov. Delivery devices in infants and young children. Diakses September 2017.
[12] Hsu W., et al. Evaluation of delivery efficiency from valved holding chambers with facemasks. Resp. Drug Delivery Europe, 2011; 2:505-510.
[13] Lung.org. Managing asthma/Valved holding chambers. Diakses September 2017.
[14] Everard ML., Clark AR., Milner AD. Drug delivery from holding chamber with facemask. Arch Dis Child, 1992; 67:580-585.
[15] Mitchell J. et al. Electrostatic and inhaled medications: Influence on delivery via pressurized metered dose inhalers and add on devices. Respiratory Care, 2000. Volume 52(3):283-300.
[16] Diadaptasi dari: Hirst, PH., et al. Deposition and pharmacokinetics of an HFA formulation of Triamcinolone Acetonide delivered by pressurized metered dose inhaler. Journal of Aerosol Medicine. 2001; Volume 14 (2):155-166.
[17] Diadaptasi dari Erzinger, S. et al. Facemask and aerosol delivery in vivo. Journal Aerosol Medicine 2007; 20 (Suppl 1):S78-S84
[18] Di antara apotek ritel yang mengklaim memiliki merek spacer yang disukai di apotek mereka. Survei online yang dilakukan pada 205 apotek ritel terdaftar.